Regulation of the Antibody Response to Pneumococcal Capsular Polysaccharides

Regulation of the Antibody Response to
Pneumococcal Capsular Polysaccharides

By Axel Jeurissen
March 2005
Leuven University Press
ISBN: 9058674487
164 pages, Illustrated, 6 Ľ" x 9 ˝"
$99.50 Paper Original

This is a Ph.D. dissertation. S. pneumoniae is a major causative agent of serious infections. Besides, the emerging resistance of S. pneumoniae to multiple antibiotic drugs is a major concern in the treatment of infections caused by this micro-organism. Therefore it is important to study the molecular mechanisms that meditate the antibody response to caps-PS.

The aim of the study is to better understand the regulation and the molecular mechanisms of the immune response to pneumococcal caps-PS. The present study was undertaken to determine the role of the CD40-CD40L interaction in the murine antibody response to pneumococcal caps-PS antigens.

Immunology
Acta Biomedica Lovaniensia, No. 332

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