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Progesterone Induces Apoptosis in Eosinophilic
Granulocytes & Induces Tumour Necrosis
Factor-Alpha / Tumour Necrosis Factor Receptor

By Joeri Aerts
June 2002
Leuven University Press
ISBN: 90-5867-216-6[book cover]
121 pages, illustrated
$58.00 paper original

Contents include:
Morphologic and functional characteristics of eosinophils. Eosinophils and disease. Eosinophils and apoptosis. Steroid receptors: classical and membrane bound. Progesterone in reproduction. The influence of progesterone on eosinophils. Progesterone as a therapeutic agent. Aims of the study. Materials and methods. Patient material and cell lines. Steroids, monoclonal antibodies and recombinant cytokines. Microscopic analyses. Real-time quantitative PCR. Cell culture analyses. Development of real-time quantitative PCR method for quantification of cytokine expression. Influence of progesterone on eosinophils. General Discussion and conclusions.

Ph.D. thesis.

Acta Biomedica Lovaniensia, No. 256