Novel Tissue-Equivalent
Proportional Counter Based
on a Gas Electron Multiplier

By Majid Farahmand
September 2004
Delft University Press
ISBN: 9040724881
156 pages, Illustrated, 6 ½" x 9 ½"
$59.50 Paper Original


This is a Ph.D. dissertation. Instruments are essential tools in science since our senses are very limited. New devices open new research possibilities for a better understanding of the laws of nature. In this work development of a new type of instrument is focused on. This device has been used to assess the impact of radiation on tissue. Radiation is a form of energy that has always been around in nature and human beings are irradiated throughout life.

To asses the impact of radiation exposure properly, it is essential to understand the mechanism of the interactions of radiation with living organisms. Based on their primary interaction mechanisms, ionizing radiation can be classified into directly ionizing charged particles and indirectly ionizing radiation. Radiation of the indirectly ionizing type deposits its energy through the production of charged particles, which are the directly ionizing type.

In the case of directly ionizing interactions of charged particles with matter, the energy is lost in a large number of relatively small interactions via the Coulomb forces causing ionizations and excitations of the atoms and molecules. In a living cell, ionization and excitation of atoms and molecules initiate a complex chain of events from chemical changes in some important bio-molecules through mutations to bio-functional changes such as transformation and cell death.

Contents include: General Introduction, Experimental Microdosimetry, Tissue-Equivalent Proportional Counter: Principles of Operation and Application, Analytical Calculations of Neutron Microdosimetric Dose Distribution, High-Energy Neutron Microdosimetry, Gas Electron Multiplier Operation with Tissue-Equivalent Gases at Various Pressures, Design of a New Tissue-Equivalent Proportional Counter Based on a Gas Electron Multiplier, Microdosimetric Measurements with a TEPC Based on a GEM, Microdosimetric Measurements with a TEPC Based on a GEM.

Radiology

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