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Interaction between S. Pneumoniae
& In Vitro Human Nasopharyngeal Epithelium

By Katrien Lagrou
June 2002
Leuven University Press
ISBN: 90-5867-220-4
122 pages, illustrated
$48.50 paper original

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Contents:
General Introduction. Pathogenesis of Pneumococcal infection. Adherence to and invasion of epithelial cells by Pneumococci. Pneumococcal virulence factors. Regulation of Pneumococcal physiological events (Transformation, adherence and lysis) as a function to the growth cycle. Aims of the study. Development of an in vitro model of human nasopharyngeal epithelium. Characterization of the epithelial cell-layer. Development of a pneumococcal adherence assay. Interaction between Pneumococci and epithelial cells in the in vitro model of human nasopharyngeal epithelium. Influence of Subinhibitory concentrations of erythromycin on pneumococcal adherence to in vitro human nasopharyngeal epithelium. Role of CBPA in pneumococcal adherence to nasopharyngeal epithelial cells.

Pathology
Acta Biomedica Lovaniensia, No. 258