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Interaction of the Protein Phosphatase-1 Regulator
NIPP1 with Pre-mRNA Splicing Factors

By An Boudrez
June 2002
Leuven University Press
ISBN: 90-5867-218-2[book cover]
116 pages, illustrated
$55.00 paper original

Introduction. Reversible protein phosphorylation. Protein Ser/Thr phosphatases of type-1. NIPP1. Pre-mRNA splicing. Aims and strategies. Materials and Methods. Results and Discussion. Characterization of the aminoterminal domain of NIPP1. Analysis of the interaction between Cdc5L and NIPP1. Analysis of the interaction between SAP155 and NIPP1. Functional characterization of the NIPP1-SAP155 and NIPP1-Cdc5L complexes. General discussion and perspectives. The role and regulation of FHA-domains. Is NIPP1 a multifunctional protein? The role of NIPP1 in pre-mRNA splicing. Summary. References.

Ph.D. thesis.

Acta Biomedica Lovaniensia, No. 257