Domain Structure & Function of Nucleotide
Pyrophosphatases/ Phosphodiesterases (NPPs)

By Rik Gijsbers
September 2003
Leuven University Press
ISBN: 90-5867-300-6
139 pages, Illustrated, 6 1/4" x 9 1/2"
$48.50 Paper Original

Contents of this Ph.D. dissertation include: Ecto-nucleotidases, Extracellular nucleotides and their metabolism, Nucleotide Pyrophosphatase/Phosphodiesterase (NPPs), Mammalian NPP isforms, NPPs are modular proteins, Enzyme activities of NPPs, Functional diversity of NPPs, Aims and strategies, Materials and methods, Results and discussions, A family of NPP proteins, Characterization of the catalytic domain of NPPs, Characterization of the non-catalytic ectodomains of NPPs, NPP1 and the pathogenesis of insulin resistance, Conclusions and Perspectives.

Acta Biomedica Lovaniensia No. 285

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